專家信息:
孔道春,男,現(xiàn)任北京大學生命科學學院教授,博士生導師。
教育及工作經(jīng)歷:
1979-1983 蘭州大學生物系,學士
1986-1989 中國科學院上海生物化學研究所,碩士
1990-1995 Temple University Medical School, USA, 博士
1995-1998 Harvard University Medical School, 博士后
1998-2000 The Memorial Sloan-Kettering Cancer Center, 博士后
2000-2005 National Institutes of Health, Bethesda, USA, 研究員
2005- 北京大學生命科學學院教授
科學研究:
研究方向:
主要研究真核細胞染色體DNA 復制起始的機理與調(diào)控、Checkpoint的激活機理及其信號傳導、Control of cell division cycle and cancer。
承擔的科研項目情況:
主持或參加科研項目多項。
科研成果:
1 質(zhì)粒RP4∷Mu引起霍亂弧菌基因的突變和轉(zhuǎn)移 蘇國富; 徐永強; 孔道春; 楊長告; 陸德如 軍事醫(yī)學科學院; 蘭州生物制品研究所; 山東醫(yī)學院; 中國科學院微生物研究所 1985-09-15
發(fā)明專利:
1 含單鏈DNA結(jié)合蛋白的融合蛋白及其表達和純化的方法 孔道春; 華余; 胡家志; 孫靜亞 2010-05-19
資料更新中……
論文專著:
發(fā)表論文:
1. Daochun Kong, Thomas R. Coleman & Melvin L. DePamphilis (2003) Xenopus origin recognition complex (ORC) initiates DNA replication preferentially at sequences targeted by Schizosaccharomyces pombe ORC. EMBO J. 22:3441-3450.
2. Daochun Kong and Melvin DePamphilis (2002) Site specific ORC binding, pre-replication complex assembly, and DNA synthesis at S. pombe replication origins. (EMB0 J. 21: 5567-5576.
3. Daochun Kong & Melvin L. DePamphilis (2001) Site-specific DNA binding of the Schizosaccharomyces pombe origin recognition complex is determined by the Orc4 subunit. MCB 21: 8095-8103.
4. K-Y. Moon, Daochun Kong, J-K Lee, S. Raychandhuri, and Jerard Hurwitz. (1999) Identification and reconstitution of the origin recognition complex from Schizosaccharomyces pombe. Proc. Natl. Acad. Sci. USA 96: 12367-12372.
5. Daochun Kong, Jack D. Griffith, and Charles C. Richardson. (1997) T7 gene 4 helicase promotes branch migration through non-homologous, mismatched, or ultraviolet-irradiated DNA regions. Proc. Natl. Acad. Sci. USA 94: 2987-2992.
6. Daochun Kong and Charles C. Richardson. (1996) Single-stranded DNA binding protein and DNA helicase of bacteriophage T7 mediate homologous DNA strand exchange. EMBO J. 15: 2010-2019.
資料更新中……